Our Objectives

Understanding the role and fate of exogenous and endogenous nanoparticles in the body

• Investigate their properties, transformations, and impact within the organism.
• Decipher intercellular communication mechanisms involving biological nanoparticles (extracellular vesicles, viral particles, mitochondria, etc.).

Developing innovative (bio)therapies

• Leverage biological nanoparticles as therapeutic vectors in nanomedicine or as alternatives to cell therapies.
• Optimize immunotherapies and other precision treatments through external physical control.
• Overcome treatment resistance mechanisms with innovative delivery strategies.

Integrating bioproduction challenges

• Develop robust, controlled, and eco-friendly processes for the production of biological nanoparticles for therapeutic use.
• Ensure the reproducibility, safety, and scalability of manufacturing processes through AI-driven optimization for industrial and clinical transfer.
• Develop quality control methods at the nanometric scale.

Facilitating the transfer of innovations to clinical applications

• Transform scientific breakthroughs into concrete medical applications.
• Bridge the gap between fundamental research and clinical trials to directly benefit patients.

Promoting an interdisciplinary and collaborative approach

• Bring together researchers in engineering, physics, biology, medicine, chemistry, and AI for an integrated approach.
• Develop partnerships with academic institutions and industry to accelerate innovation.

Addressing global and planetary health challenges

• Contribute to disease prevention and treatment by developing safer, more effective, and more targeted therapies.
• Integrate environmental and ethical considerations into the development of nanomedicines and bioprocesses.

The NABI Laboratory is committed to pushing the boundaries of nanomedicine to make biotherapies accessible to all and to secure their large-scale production.