Nabi – Nanomédecine, Biologie Extracellulaire, Intégratome et Innovations en Santé
NABI Laboratory: Mission and Objectives
The NABI Laboratory (Nanomedicine, Extracellular Biology, Integratome, and Health Innovations), established on January 1, 2025, by Université Paris Cité, CNRS, and INSERM, aims to develop next-generation therapeutic approaches and make them accessible to the greatest number of patients.
Through interdisciplinary research and our technology accelerator, the IVETh Bioproduction and Biotherapy Integrator, our ambition is to democratize biotherapies and de-risk their bioproduction.
Our Objectives
Understanding the role and fate of exogenous and endogenous nanoparticles in the body
- Investigate their properties, transformations, and impact within the organism.
- Decipher intercellular communication mechanisms involving biological nanoparticles (extracellular vesicles, viral particles, mitochondria, etc.).
Developing innovative (bio)therapies
- Leverage biological nanoparticles as therapeutic vectors in nanomedicine or as alternatives to cell therapies.
- Optimize immunotherapies and other precision treatments through external physical control.
- Overcome treatment resistance mechanisms with innovative delivery strategies.
Integrating bioproduction challenges
- Develop robust, controlled, and eco-friendly processes for the production of biological nanoparticles for therapeutic use.
- Ensure the reproducibility, safety, and scalability of manufacturing processes through AI-driven optimization for industrial and clinical transfer.
- Develop quality control methods at the nanometric scale.
Facilitating the transfer of innovations to clinical applications
- Transform scientific breakthroughs into concrete medical applications.
- Bridge the gap between fundamental research and clinical trials to directly benefit patients.
Promoting an interdisciplinary and collaborative approach
- Bring together researchers in engineering, physics, biology, medicine, chemistry, and AI for an integrated approach.
- Develop partnerships with academic institutions and industry to accelerate innovation.
Addressing global and planetary health challenges
- Contribute to disease prevention and treatment by developing safer, more effective, and more targeted therapies.
- Integrate environmental and ethical considerations into the development of nanomedicines and bioprocesses.
The NABI Laboratory is committed to pushing the boundaries of nanomedicine to make biotherapies accessible to all and to secure their large-scale production.
News
Lucile Alexandre lauréate du programme MEDNIGHT
Lucile Alexandre participe vendredi 14 février 2025 à la table ronde du Learning Planet Institute, 8 bis rue Charles V, 75004 Paris, sur les femmes en sciences. Lucile a également été sélectionnée pour le projet MEDNIGHT, mettant en avant les femmes scientifiques méditerranéennes.
Florence Gazeau élue à l’Académie des Sciences
Shéryl Bui Lauréate du Prix UNESCO-L’Oréal Jeunes Talents (France)
Shéryl Bui, post doc au laboratoire MSC, a reçu le prix L’Oréal UNESCO Jeunes Talents 2024, dans la mention biotechnologie pour la santé.
Seminar – “RelB Activation and Metabolic Reprogramming in Cancer Cells”
Seminar by Véronique Baud (group « NF-kB, Différenciation et Cancer », UPR7324,Université Paris Cité, IP2S), October 11st 2024, 11am, room Leduc
MSCmed participe à l’alliance ERDERA de recherche sur les maladies rares
L’Alliance ERDERA (European Rare Disease Research Alliance), regroupant 170 institutions, a été inaugurée début septembre 2024
Seminar – “Why have biologists from the ICE unit (VetAgro Sup Lyon) established a close collaboration with physicists for the past 15 years?”
Seminar by Pierre BRUYERE (MCU, ICE Unit, VetAgro Sup Lyon), September 24th 2024, 12pm inLavoisier A
Seminar – “The Suspended Micro-Nanochannel Resonator”
Seminar by Vincent Agache on the Tuesday, February 18th, at 12pm in Rabelais 2. Topic: "The Suspended Micro-Nanochannel Resonator"
Seminar – “Multiple Roles of Hyaluronan in Extracellular Vesicle Biology” and “Pharmacokinetics of Nanomedicines in the Eye: Implications for Extracellular Vesicle Treatments”
Seminar by Kirsi Rilla and Arto Urtti on the Tuesday, March 7th, at 12pm in Room Rabelais 2. Topic: Kirsi Rilla will discuss "Multiple Roles of Hyaluronan in Extracellular Vesicle Biology," and Arto Urtti will present on "Pharmacokinetics of Nanomedicines in the...
Seminar – “Deep Molecular Characterization of Extracellular Vesicles as Sources for Low-Invasive Indicators for Pathophysiology”
Seminar by Juan Manuel Falcon-Perez on the Tuesday, February 6th, at 12pm in Salle des thèses . Topic: "Deep Molecular Characterization of Extracellular Vesicles as Sources for Low-Invasive Indicators for Pathophysiology"
Seminar – “Therapeutic strategies for carcinomas”
Seminar by Professor Jean Paul Thiery on the Tuesday, February 27th, at 12pm in Room R229 . Topic: "Therapeutic strategies for carcinomas"